Studie: Chronische Virusinfektionen bei myalgischer Enzephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Verfasst: 11. Februar 2019, 11:08
Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Santa Rasa,1 Zaiga Nora-Krukle,1 Nina Henning,2 Eva Eliassen,2 Evelina Shikova,4 Thomas Harrer,5 Carmen Scheibenbogen,6 Modra Murovska,1 Bhupesh K. Prusty,corresponding author2,3 and the European Network on ME/CFS (EUROMENE), J Transl Med. 2018; 16: 268., doi: 10.1186/s12967-018-1644-y
Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Santa Rasa,1 Zaiga Nora-Krukle,1 Nina Henning,2 Eva Eliassen,2 Evelina Shikova,4 Thomas Harrer,5 Carmen Scheibenbogen,6 Modra Murovska,1 Bhupesh K. Prusty,corresponding author2,3 and the European Network on ME/CFS (EUROMENE), J Transl Med. 2018; 16: 268., doi: 10.1186/s12967-018-1644-y
Abstract
Background and main text
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and controversial clinical condition without having established causative factors. Increasing numbers of cases during past decade have created awareness among patients as well as healthcare professionals. Chronic viral infection as a cause of ME/CFS has long been debated. However, lack of large studies involving well-designed patient groups and validated experimental set ups have hindered our knowledge about this disease. Moreover, recent developments regarding molecular mechanism of pathogenesis of various infectious agents cast doubts over validity of several of the past studies.
Conclusions
This review aims to compile all the studies done so far to investigate various viral agents that could be associated with ME/CFS. Furthermore, we suggest strategies to better design future studies on the role of viral infections in ME/CFS.
Keywords: ME/CFS, Viral infections, Biomarkers
Schlussfolgerungen
Diese Überprüfung zielt darauf ab, alle bisher durchgeführten Studien zusammenzustellen, um verschiedene virale Wirkstoffe zu untersuchen, die mit ME/CFS in Verbindung gebracht werden könnten. Darüber hinaus schlagen wir Strategien zur besseren Gestaltung zukünftiger Studien über die Rolle von Virusinfektionen bei ME/CFS vor.
Übersetzt mit www.DeepL.com/Translator